Bee Venom Extract

INCI: BEE VENOM EXTRACT

CAS Number
Not assigned (complex biological mixture); apitoxin referenced under CAS 20449-79-0 (melittin component)
Function
Skin conditioning, anti-aging
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with no specific restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major allergen requiring on-pack allergen warning in many markets; cross-reactivity with wasp venom; batch-to-batch variability in peptide content; not suitable for sensitive-skin claims.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Bee Venom Extract safe in cosmetics?

Major allergen requiring on-pack allergen warning in many markets; cross-reactivity with wasp venom; batch-to-batch variability in peptide content; not suitable for sensitive-skin claims. The EU classifies Bee Venom Extract as "restricted". Safety rating: MODERATE.

Is Bee Venom Extract allowed in the EU?

Bee Venom Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bee Venom Extract do in cosmetics?

Bee Venom Extract functions as: Skin conditioning, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex biological mixture); apitoxin referenced under CAS 20449-79-0 (melittin component).

What is the Margin of Safety for Bee Venom Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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