Bergenia Crassifolia Leaf Extract

INCI: BERGENIA CRASSIFOLIA LEAF EXTRACT

CAS Number
Not specifically assigned; generic *Bergenia crassifolia* extracts may reference 93164-91-1
Function
Antioxidant, anti-inflammatory, adaptogenic, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA monograph; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Extract contains arbutin (15โ€“20%) with hydroquinone metabolite concerns, bergapten with furocoumarin phototoxicity risk, pyrogallol as skin irritant, and hydroquinone as direct constituent triggering EU Annex II restrictions at non-trace levels.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Bergenia Crassifolia Leaf Extract safe in cosmetics?

Extract contains arbutin (15โ€“20%) with hydroquinone metabolite concerns, bergapten with furocoumarin phototoxicity risk, pyrogallol as skin irritant, and hydroquinone as direct constituent triggering EU Annex II restrictions at non-trace levels. The EU classifies Bergenia Crassifolia Leaf Extract as "restricted". Safety rating: MODERATE.

Is Bergenia Crassifolia Leaf Extract allowed in the EU?

Bergenia Crassifolia Leaf Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bergenia Crassifolia Leaf Extract do in cosmetics?

Bergenia Crassifolia Leaf Extract functions as: Antioxidant, anti-inflammatory, adaptogenic, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned; generic *Bergenia crassifolia* extracts may reference 93164-91-1.

What is the Margin of Safety for Bergenia Crassifolia Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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