Bergenin

INCI: BERGENIN

CAS Number
477-90-7
Function
Skin conditioning (antioxidant, anti-inflammatory, wound healing); C-glucoside of 4-O-methyl gallic acid
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA monograph; no CIR review; not GRAS-listed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

As a pure chemical (not crude extract), purity specification and heavy metal limits required in CPSR. GHS H315: Causes skin irritation; GHS H319: Causes serious eye irritation; GHS H335: May cause respiratory irritation.

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Concern Level: Moderate

Frequently Asked Questions

Is Bergenin safe in cosmetics?

As a pure chemical (not crude extract), purity specification and heavy metal limits required in CPSR. GHS H315: Causes skin irritation; GHS H319: Causes serious eye irritation; GHS H335: May cause respiratory irritation. The EU classifies Bergenin as "prohibited". Safety rating: MODERATE.

Is Bergenin allowed in the EU?

Bergenin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Bergenin do in cosmetics?

Bergenin functions as: Skin conditioning (antioxidant, anti-inflammatory, wound healing); C-glucoside of 4-O-methyl gallic acid. It is classified as a cosmetic ingredient in our database. CAS number: 477-90-7.

What is the Margin of Safety for Bergenin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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