Betulinyl Methoxy PEG-22 Carboxylate

INCI: BETULINYL METHOXY PEG-22 CARBOXYLATE

CAS Number
Not publicly assigned in CosIng (PEG derivative; supplier-specific)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Allowed - no specific prohibition; falls under general cosmetic ingredient safety provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PEG derivatives are generally well tolerated; a 2005 safety assessment by Fruijtier-Pölloth concluded PEGs and their derivatives are safe as used in cosmetics. Potential concern for 1,4-dioxane contamination as an ethoxylation byproduct (trace-level impurity in PEG compounds). A betulin (birch bark-derived triterpene) conjugated with PEG-22 to enhance water solubility and skin bioavailability; PEGs with higher molecular weights act as consistency enhancers and humectants

⚠️
Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Betulinyl Methoxy PEG-22 Carboxylate safe in cosmetics?

PEG derivatives are generally well tolerated; a 2005 safety assessment by Fruijtier-Pölloth concluded PEGs and their derivatives are safe as used in cosmetics. Potential concern for 1,4-dioxane contamination as an ethoxylation byproduct (trace-level impurity in PEG compounds). A betulin (birch bark-derived triterpene) conjugated with PEG-22 to enhance water solubility and skin bioavailability; PEGs with higher molecular weights act as consistency enhancers and humectants The EU classifies Betulinyl Methoxy PEG-22 Carboxylate as "restricted". Safety rating: MODERATE.

Is Betulinyl Methoxy PEG-22 Carboxylate allowed in the EU?

Betulinyl Methoxy PEG-22 Carboxylate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Betulinyl Methoxy PEG-22 Carboxylate do in cosmetics?

Betulinyl Methoxy PEG-22 Carboxylate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned in CosIng (PEG derivative; supplier-specific).

What is the Margin of Safety for Betulinyl Methoxy PEG-22 Carboxylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Betulinyl Methoxy PEG-22 Carboxylate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Betulinyl Methoxy PEG-22 Carboxylate in your formulation.