Biotin/Mouse Fibroblast Conditioned Media

INCI: BIOTIN/MOUSE FIBROBLAST CONDITIONED MEDIA

CAS Number
Not specifically assigned (complex biological mixture)
Function
Skin conditioning (growth factor delivery, anti-aging)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited; classified as a cosmetic ingredient; however, products making drug-like claims (e.g., "stimulates collagen synthesis") may trigger drug classification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential allergenicity from murine (mouse)-derived proteins; batch-to-batch variability of growth factor content; sterility and bioburden control critical; consumer perception issues with animal-derived ingredients. Conditioned media from mouse fibroblast culture contains a cocktail of growth factors, cytokines, and extracellular vesicles (including exosomes) that promote collagen biosynthesis, protect against oxidative stress, and support skin rejuvenation; biotin (vitamin B7) is included a...

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Biotin/Mouse Fibroblast Conditioned Media safe in cosmetics?

Potential allergenicity from murine (mouse)-derived proteins; batch-to-batch variability of growth factor content; sterility and bioburden control critical; consumer perception issues with animal-derived ingredients. Conditioned media from mouse fibroblast culture contains a cocktail of growth factors, cytokines, and extracellular vesicles (including exosomes) that promote collagen biosynthesis, protect against oxidative stress, and support skin rejuvenation; biotin (vitamin B7) is included a... The EU classifies Biotin/Mouse Fibroblast Conditioned Media as "permitted". Safety rating: MODERATE.

Is Biotin/Mouse Fibroblast Conditioned Media allowed in the EU?

Biotin/Mouse Fibroblast Conditioned Media EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Biotin/Mouse Fibroblast Conditioned Media do in cosmetics?

Biotin/Mouse Fibroblast Conditioned Media functions as: Skin conditioning (growth factor delivery, anti-aging). It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (complex biological mixture).

What is the Margin of Safety for Biotin/Mouse Fibroblast Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Biotin/Mouse Fibroblast Conditioned Media in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Biotin/Mouse Fibroblast Conditioned Media in your formulation.