Biotinoyl Pentapeptide-4

INCI: BIOTINOYL PENTAPEPTIDE-4

CAS Number
Not publicly assigned / not listed in CosIng or major databases
Function
Anti-sebum (inhibits sebum production), antimicrobial, antioxidant, hair conditioning, skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibitions or restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No major safety red flags documented; generally well-tolerated; potential for mild irritation in hypersensitive individuals. Synthetic biotin-pentapeptide-4 conjugate (also known as Biotinyl-GHK); multi-functional - regulates sebum, provides antimicrobial action, and strengthens skin barrier

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Concern Level: Moderate

Frequently Asked Questions

Is Biotinoyl Pentapeptide-4 safe in cosmetics?

No major safety red flags documented; generally well-tolerated; potential for mild irritation in hypersensitive individuals. Synthetic biotin-pentapeptide-4 conjugate (also known as Biotinyl-GHK); multi-functional - regulates sebum, provides antimicrobial action, and strengthens skin barrier The EU classifies Biotinoyl Pentapeptide-4 as "permitted". Safety rating: MODERATE.

Is Biotinoyl Pentapeptide-4 allowed in the EU?

Biotinoyl Pentapeptide-4 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Biotinoyl Pentapeptide-4 do in cosmetics?

Biotinoyl Pentapeptide-4 functions as: Anti-sebum (inhibits sebum production), antimicrobial, antioxidant, hair conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned / not listed in CosIng or major databases.

What is the Margin of Safety for Biotinoyl Pentapeptide-4?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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