Bis-Acryloyl Poloxamer 407

INCI: BIS-ACRYLOYL POLOXAMER 407

CAS Number
Not individually assigned; Poloxamer 407 parent CAS: 9003-11-6
Function
Emulsion Stabilizer, Film Former
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Poloxamer 407 is FDA-approved excipient for pharmaceutical use; the bis-acryloyl derivative is cosmetic-grade

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual acrylic monomer content is the primary concern. Acrylates are EU Annex III entry for nail products. Supplier must provide residual monomer specification (target <10 ppm). Synthetic origin. Request polymerization completion certificate

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Concern Level: Moderate

Frequently Asked Questions

Is Bis-Acryloyl Poloxamer 407 safe in cosmetics?

Residual acrylic monomer content is the primary concern. Acrylates are EU Annex III entry for nail products. Supplier must provide residual monomer specification (target <10 ppm). Synthetic origin. Request polymerization completion certificate The EU classifies Bis-Acryloyl Poloxamer 407 as "restricted". Safety rating: MODERATE.

Is Bis-Acryloyl Poloxamer 407 allowed in the EU?

Bis-Acryloyl Poloxamer 407 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-Acryloyl Poloxamer 407 do in cosmetics?

Bis-Acryloyl Poloxamer 407 functions as: Emulsion Stabilizer, Film Former. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned; Poloxamer 407 parent CAS: 9003-11-6.

What is the Margin of Safety for Bis-Acryloyl Poloxamer 407?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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