NOAEL Studies Cosmetic Ingredient

Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane NOAEL Studies

INCI: BIS(BUTYLBENZOATE) DIAMINOTRIAZINE AMINOPROPYLTRISILOXANE

CAS: 207562-42-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 9 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =1 % human oral - NOAEL study p.28
SCCS Opinion NOAEL =1.34 mg/kg bw/day rat oral 13 week NOAEL study p.29
SCCS Opinion NOAEL =3.3 - human oral - NOAEL study p.28
SCCS Opinion NOAEL =4.46 % human oral - NOAEL study p.29
SCCS Opinion NOAEL =8 - human oral - NOAEL study p.28
SCCS Opinion NOAEL =10 - - oral 10 months NOAEL study p.25
SCCS Opinion NOAEL =100 % rat oral 13 week NOAEL study p.29
SCCS Opinion NOAEL =1000 mg/kg bw/day rat oral Sub-chronic repeated dose toxicity p.17
SCCS Opinion NOAEL =1000 mg/kg bw/d - oral 28 day genotoxicity p.18
Regulatory source 16 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 1 % human oral - - p.28
Regulatory source - 1.34 mg/kg bw/day rat oral 13 week - p.29
Regulatory source - 3.3 - human oral - - p.28
Regulatory source - =4.46 % human oral - - p.29
Regulatory source - 8 - human oral - - p.28
Regulatory source - 10 - - oral 10 months - p.25
Regulatory source - 10 % - oral 90-day - p.31
Regulatory source - 100 % rat oral 13 week - p.29
Regulatory source - 1000 mg/kg bw/d - oral - - p.28
Regulatory source - 1000 mg/kg bw/d - oral 90 day - p.28
Regulatory source - =1000 mg/kg bw/d rat oral 13 week - p.29
Regulatory source developmental toxicity 1000 mg/kg bw/day - - developmental developmental toxicity p.24
Regulatory source genotoxicity 1000 mg/kg bw/d - oral 28 day genotoxicity p.18
Regulatory source genotoxicity 1000 mg/kg bw/d mouse oral 4 week genotoxicity p.30
Regulatory source repeated dose toxicity 1000 mg/kg bw/day rat oral Sub-chronic repeated dose toxicity p.17
Regulatory source reproductive toxicity 1000 mg/kg bw/d - oral 90 day reproductive toxicity p.31
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 50I65NU3DV UNII - - - chemical -