NOAEL Studies Cosmetic Ingredient

Bishydroxyethyl Biscetyl Malonamide NOAEL Studies

INCI: BISHYDROXYETHYL BISCETYL MALONAMIDE

CAS: 149591-38-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 150 mg/kg bw/day rat oral 28 day Short Term Toxicity SCCP; Lea L & Spurgeon M (1994) Pseudoceramide H: 28-Day Subacute Oral Toxicity Study inRats, Project No. GF930518, EnvironmentalSafety Laboratory, Unilever Research,Bedford, England
COSMOS DB NOAEL 15 mg/kg bw/day rat oral 28 day Short Term Toxicity SCCP; Lea L & Spurgeon M (1994) Pseudoceramide H: 28-Day Subacute Oral Toxicity Study inRats, Project No. GF930518, EnvironmentalSafety Laboratory, Unilever Research,Bedford, England
SCCS Opinion 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =15 mg/kg/day - oral Sub-chronic repeated dose toxicity p.11
Regulatory source 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source repeated dose toxicity 15 mg/kg/day - oral Sub-chronic repeated dose toxicity p.11
Regulatory source repeated dose toxicity 15 mg/kg/day rat oral 28-day repeated dose toxicity p.20
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 913CU8H33E UNII - - - chemical -