Is Bronopol safe in cosmetics?
Bronopol has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Preservative
Bronopol
INCI: BRONOPOL
Bronopol (CAS 52-51-7) is a cosmetic preservative functioning as Preservative. EU Regulation 1223/2009 status: restricted, max 0.1%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 52-51-7 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.1%
US US Status
restricted
US Notes
Washington State banned effective January 1, 2027 (August 2025 rule, WAC 246-930). No federal cosmetic concentration limit. CIR assessed safe at 0.01% or less in leave-on products and 0.1% or less in rinse-off products. Dual hazard: formaldehyde release and nitrosamine formation with secondary amines in formulation.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bronopol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Bronopol.
Regulatory Flags
formaldehyde-releaser
nitrosamine-precursor
iarc-group-1-related
contact-allergen
preservative
washington-state-ban-2027
eu-restricted
annex-v
federal-ban-pending
children-restricted-eu
dual-hazard
endocrine_disruptor
eu_children_restricted
eu_cosing_listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BRONOPOL
ChEMBL ID
CHEMBL1408862
Max Phase
2
Frequently Asked Questions
Is Bronopol allowed in the EU?
Bronopol EU regulatory status: restricted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Bronopol do in cosmetics?
Bronopol functions as: Preservative. It is classified as a Preservative in our database. CAS number: 52-51-7.
Is Bronopol used outside cosmetics?
Bronopol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Bronopol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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