Bryonolic Acid

INCI: BRYONOLIC ACID

CAS Number
24480-45-3
Function
Skin Conditioning (anti-inflammatory, antioxidant)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not established โ€” No published NOAEL, SED, or dermal absorption study for cosmetic exposure calculation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient toxicological data for standalone CPSR justification; pharmacological activity (iNOS suppression, Ca2+ channel modulation) requires safety argument at cosmetic-use concentrations

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Concern Level: Moderate

Frequently Asked Questions

Is Bryonolic Acid safe in cosmetics?

Insufficient toxicological data for standalone CPSR justification; pharmacological activity (iNOS suppression, Ca2+ channel modulation) requires safety argument at cosmetic-use concentrations The EU classifies Bryonolic Acid as "permitted". Safety rating: MODERATE.

Is Bryonolic Acid allowed in the EU?

Bryonolic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bryonolic Acid do in cosmetics?

Bryonolic Acid functions as: Skin Conditioning (anti-inflammatory, antioxidant). It is classified as a cosmetic ingredient in our database. CAS number: 24480-45-3.

What is the Margin of Safety for Bryonolic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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