Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
9 study endpoints found for C10-16 Pareth-1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=500 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | other | rat | oral | REACH |
| NOAEL | >=500 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
1,4-Dioxane residual contamination must be tested (≤10 ppm per industry standard). Ethylene oxide residuals must be below detection limits.
Regulatory Flags
Frequently Asked Questions
Is C10-16 Pareth-1 safe in cosmetics?
1,4-Dioxane residual contamination must be tested (≤10 ppm per industry standard). Ethylene oxide residuals must be below detection limits. The EU classifies C10-16 Pareth-1 as "permitted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.
Is C10-16 Pareth-1 allowed in the EU?
C10-16 Pareth-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does C10-16 Pareth-1 do in cosmetics?
C10-16 Pareth-1 functions as: Cleansing, Skin conditioning – Emollient, Surfactant – Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68002-97-1.
What is the Margin of Safety for C10-16 Pareth-1?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for C10-16 Pareth-1?
The NOAEL (No Observed Adverse Effect Level) for C10-16 Pareth-1 is >=500 mg/kg bw/day based on a oral study via oral route in rat. A total of 9 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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