C12-15 Pareth-5
INCI: C12-15 PARETH-5 (BEING UPDATED TO C12-15 ALKETH-5 PER INCI NOMENCLATURE REVISION)
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for C12-15 Pareth-5. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Potential residual 1,4-dioxane from ethoxylation process (a known contaminant of concern, especially in NY/CA); mild skin/eye irritation at high concentrations. Non-ionic surfactant with strong detergency, emulsifying, and dispersing power. Readily biodegradable per EC Regulation 648/2004. Low foaming relative to other ethoxylated alcohols
Regulatory Flags
Frequently Asked Questions
Is C12-15 Pareth-5 safe in cosmetics?
Potential residual 1,4-dioxane from ethoxylation process (a known contaminant of concern, especially in NY/CA); mild skin/eye irritation at high concentrations. Non-ionic surfactant with strong detergency, emulsifying, and dispersing power. Readily biodegradable per EC Regulation 648/2004. Low foaming relative to other ethoxylated alcohols The EU classifies C12-15 Pareth-5 as "permitted". Safety rating: MODERATE. 6 toxicological study endpoint(s) are available in our database.
Is C12-15 Pareth-5 allowed in the EU?
C12-15 Pareth-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does C12-15 Pareth-5 do in cosmetics?
C12-15 Pareth-5 functions as: Surfactant - cleansing; surfactant - emulsifying; fragrance functional ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 68131-39-5.
What is the Margin of Safety for C12-15 Pareth-5?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for C12-15 Pareth-5?
The NOAEL (No Observed Adverse Effect Level) for C12-15 Pareth-5 is >=500 mg/kg bw/day based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.
Compliance Tools
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