Caesalpinia Sappan Bark Extract

INCI: CAESALPINIA SAPPAN BARK EXTRACT

CAS Number
89958-14-5
Function
Skin conditioning, antioxidant, colorant (natural red dye), anti-inflammatory
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA or CIR formal safety assessment on file; used as a natural colorant and skin conditioner in cosmetics without specific concentration restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Caesalpinia Sappan Bark Extract is a natural plant-derived ingredient used in cosmetics for skin conditioning, antioxidant benefit, and as a natural red colorant (brazilin-based, an alternative to carmine). Registered in EU CosIng as a skin conditioning agent with no Annex restrictions. The key active constituent, brazilin, demonstrates antioxidant, anti-inflammatory, and anti-melanogenic effects. A documented case of contact dermatitis caused by brazilin warrants a moderate sensitization flag. No carcinogenicity, reproductive toxicity, or systemic safety signals identified. Overall profile is favorable for a plant extract with standard use levels.

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Concern Level: Low

Regulatory Flags

plant-derived natural-colorant antioxidant anti-inflammatory skin-conditioning sensitization-potential limited-safety-data brazilin-active

Frequently Asked Questions

Is Caesalpinia Sappan Bark Extract safe in cosmetics?

Caesalpinia Sappan Bark Extract is a natural plant-derived ingredient used in cosmetics for skin conditioning, antioxidant benefit, and as a natural red colorant (brazilin-based, an alternative to carmine). Registered in EU CosIng as a skin conditioning agent with no Annex restrictions. The key active constituent, brazilin, demonstrates antioxidant, anti-inflammatory, and anti-melanogenic effects. A documented case of contact dermatitis caused by brazilin warrants a moderate sensitization flag. No carcinogenicity, reproductive toxicity, or systemic safety signals identified. Overall profile is favorable for a plant extract with standard use levels. The EU classifies Caesalpinia Sappan Bark Extract as "permitted". Safety rating: GOOD.

Is Caesalpinia Sappan Bark Extract allowed in the EU?

Caesalpinia Sappan Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Caesalpinia Sappan Bark Extract do in cosmetics?

Caesalpinia Sappan Bark Extract functions as: Skin conditioning, antioxidant, colorant (natural red dye), anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 89958-14-5.

What is the Margin of Safety for Caesalpinia Sappan Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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