NOAEL Studies Cosmetic Ingredient

Calcium Stearate NOAEL Studies

INCI: CALCIUM STEARATE

CAS: 1592-23-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - developmental QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabf4e4b0a7c65d1bca00; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/18930/7/9/3?documentUUID=e491bb11-2f9e-4a7b-8d80-ff69a43669a2; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=fetus: reduction in number of live offspring|fetus: changes in sex ratio|fetus: changes in postnatal survival|fetus: external malformations; TOXICOLOGICAL_EFFECT_CATEGORY=development; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15824427_15824428:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_4fc4bec5a381cf790900b5bcf5d54829
ToxValDB_ECHA_IUCLID NOAEL =2000 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaebee4b0a7c65d1cacb1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20794/7/6/2?documentUUID=cc62c15f-6c51-4b9b-8c70-adc5e09be635; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15847356_15847745_15848721:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_c569f294b4ce765ef4bcdbafe5ad0dd0
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =32.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15630543:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f318a91c6c79f880abe0047c59c33ec5
ToxValDB_HPVIS 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_HPVIS NOAEL =2000 mg/kg bw/day Rat dermal subchronic; 13 weeks subchronic LONG_REF=Thirteen-week dermal administration of Generic Calcium Complex Grease to rats. 1988. Mobil Environmental and Health Science Laboratory Final Report 60041.; TITLE=Thirteen-week dermal administration of Generic Calcium Complex Grease to rats. 1988. Mobil Environmental and Health Science Laboratory Final Report 60041; AUTHOR=Mobil Environmental and Health Science Laboratory; QUALITY=1; EXTERNAL_SOURCE_ID=64246; EXTERNAL_SOURCE_ID_DESC=HPVIS ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/63861d6de4b04f6bb1480596; RECORD_SOURCE_LEVEL=Extraction document; YEAR=1986; ORIGINAL_YEAR=1986; STUDY_GROUP=HPVIS:15639497:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_da6ea4537594dcf921a4820ba538a965
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 776XM7047L UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Ca","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"776XM7047L"}
openFDA substances FDA UNII substance identifier 776XM7047L UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Ca","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"776XM7047L"}
openFDA substances FDA UNII substance identifier 776XM7047L UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Ca","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"776XM7047L"}
openFDA substances FDA UNII substance identifier 776XM7047L UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Ca","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"776XM7047L"}