Camellia Sinensis Catechins

INCI: CAMELLIA SINENSIS CATECHINS

CAS Number
Not individually assigned to the mixture; parent CAS 84650-60-2; EGCG individually: 989-51-5
Function
Antioxidant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Favorable by dietary comparison — Oral tea consumption delivers far greater systemic exposure than cosmetic use. CIR used this as basis for systemic safety. Formal SCCS-style MoS not published; calculate per product for CPSR.

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Must confirm nonsensitizing at use concentration with HRIPT recommended. Quercetin constituent is genotoxic in vitro though non-genotoxic in oral in vivo studies. EGCG cytotoxic at ≥250 µg/mL in vitro. Multiple botanical stacking increases cumulative sensitization risk if other catechin/polyphenol-containing botanicals are present in formula.

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Concern Level: Moderate

Regulatory Flags

potential-allergen natural-origin

Frequently Asked Questions

Is Camellia Sinensis Catechins safe in cosmetics?

Must confirm nonsensitizing at use concentration with HRIPT recommended. Quercetin constituent is genotoxic in vitro though non-genotoxic in oral in vivo studies. EGCG cytotoxic at ≥250 µg/mL in vitro. Multiple botanical stacking increases cumulative sensitization risk if other catechin/polyphenol-containing botanicals are present in formula. The EU classifies Camellia Sinensis Catechins as "permitted". Safety rating: GOOD.

Is Camellia Sinensis Catechins allowed in the EU?

Camellia Sinensis Catechins EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Camellia Sinensis Catechins do in cosmetics?

Camellia Sinensis Catechins functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned to the mixture; parent CAS 84650-60-2; EGCG individually: 989-51-5.

What is the Margin of Safety for Camellia Sinensis Catechins?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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