Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis

INCI: CANNABIDIOL (WITH COSING QUALIFIER: "DERIVED FROM EXTRACT OR TINCTURE OR RESIN OF CANNABIS")

CAS Number
13956-29-1
Function
Skin conditioning; antioxidant; anti-inflammatory (skin protectant)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status restricted
US Notes Effectively restricted - the FDA considers CBD a drug ingredient (approved as Epidiolex) and has maintained that it cannot be lawfully marketed in cosmetics under the FD\&C Act's drug exclusion provision, though enforcement has been inconsistent

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

SCCS (2025) preliminary opinion considers CBD safe up to 0.19% concentration in dermal and oral cosmetic products when purity is assured. Key concerns include residual THC contamination, variable quality of natural extracts, and interaction with the endocannabinoid system. This specific CosIng entry distinguishes CBD derived from prohibited cannabis preparations (extracts/tinctures/resins) from synthetically produced CBD or hemp seed derivatives. The source of CBD determines legality - not th...

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis safe in cosmetics?

SCCS (2025) preliminary opinion considers CBD safe up to 0.19% concentration in dermal and oral cosmetic products when purity is assured. Key concerns include residual THC contamination, variable quality of natural extracts, and interaction with the endocannabinoid system. This specific CosIng entry distinguishes CBD derived from prohibited cannabis preparations (extracts/tinctures/resins) from synthetically produced CBD or hemp seed derivatives. The source of CBD determines legality - not th... The EU classifies Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis as "prohibited". Safety rating: MODERATE.

Is Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis allowed in the EU?

Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis do in cosmetics?

Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis functions as: Skin conditioning; antioxidant; anti-inflammatory (skin protectant). It is classified as a cosmetic ingredient in our database. CAS number: 13956-29-1.

What is the Margin of Safety for Cannabidiol – Derived from Extract or Tincture or Resin of Cannabis?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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