Cannabinoids

INCI: CANNABINOIDS

CAS Number
No single CAS — umbrella term covering 100+ compounds (THC: 1972-08-3; CBD: 13956-29-1; CBG: 25654-31-3; CBN: 521-35-7, etc.)
Function
Skin conditioning, antioxidant, anti-inflammatory
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status restricted
US Notes FDA drug exclusion applies to CBD and THC investigated as drugs. Other cannabinoids (CBG, CBN) in regulatory gray zone. No CIR assessment available for the class.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

This is not a valid single INCI entry for CPSR purposes. Must specify the exact cannabinoid, CAS number, source (synthetic vs. botanical), and purity. Any THC content is prohibited under Annex II. Each cannabinoid requires individual toxicological assessment.

⚠️
Concern Level: High

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Cannabinoids safe in cosmetics?

This is not a valid single INCI entry for CPSR purposes. Must specify the exact cannabinoid, CAS number, source (synthetic vs. botanical), and purity. Any THC content is prohibited under Annex II. Each cannabinoid requires individual toxicological assessment. The EU classifies Cannabinoids as "prohibited". Safety rating: MODERATE.

Is Cannabinoids allowed in the EU?

Cannabinoids EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cannabinoids do in cosmetics?

Cannabinoids functions as: Skin conditioning, antioxidant, anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS — umbrella term covering 100+ compounds (THC: 1972-08-3; CBD: 13956-29-1; CBG: 25654-31-3; CBN: 521-35-7, etc.).

What is the Margin of Safety for Cannabinoids?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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