NOAEL Studies Emollient

Caprylic Acid NOAEL Studies

INCI: CAPRYLIC ACID

CAS: 124-07-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS_DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS_DB NOAEL 1125 mg/kg bw/day rat oral 10 day Developmental US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
NTP_ICE_adme_parameters 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_adme_parameters Clint 5.626 uL/min/10^6 cells Human - - Measured; httk, Human Hepatic Intrinsic Clearance sheet=Data; excel_row=1192; Record_ID=adme_parameters_1139; Data_Type=Measured; DTXSID=DTXSID3021645; Assay=httk, Human Hepatic Intrinsic Clearance; Endpoint=Clint; Response=5.626; Response_Unit=ul/min/10^6 cells; Species=Human; Reference=httk2.3.1, Paini 2020; URL=https://cran.r-project.org/web/packages/httk/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_adme_parameters Fu 0 fraction Human - - Measured; httk, Human Plasma Fraction Unbound sheet=Data; excel_row=1191; Record_ID=adme_parameters_1139; Data_Type=Measured; DTXSID=DTXSID3021645; Assay=httk, Human Plasma Fraction Unbound; Endpoint=Fu; Response=0.0; Response_Unit=Unitless Fraction; Species=Human; Reference=httk2.3.1, Paini 2020; URL=https://cran.r-project.org/web/packages/httk/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_endocrine 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_endocrine AC50 22.1030149415202 uM - - - ERPathway2016; ER Pathway Model, Agonist sheet=Integrated_approaches; excel_row=12570; RecordID=ERPathway2016_35; DatasetName=ERPathway2016; DTXSID=DTXSID3021645; Assay=ER Pathway Model, Agonist; Endpoint=AC50; Response=22.1030149415202; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_endocrine ACC 27.5774384180333 uM - - - ERPathway2016; ER Pathway Model, Agonist sheet=Integrated_approaches; excel_row=12571; RecordID=ERPathway2016_35; DatasetName=ERPathway2016; DTXSID=DTXSID3021645; Assay=ER Pathway Model, Agonist; Endpoint=ACC; Response=27.5774384180333; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=12566; RecordID=ARPathway2016_729; DatasetName=ARPathway2016; DTXSID=DTXSID3021645; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_endocrine Model Score 0.00457 unitless - - - ERPathway2016; ER Pathway Model, Agonist sheet=Integrated_approaches; excel_row=12572; RecordID=ERPathway2016_35; DatasetName=ERPathway2016; DTXSID=DTXSID3021645; Assay=ER Pathway Model, Agonist; Endpoint=Model Score; Response=0.00457; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_endocrine Model Score 0.0142 unitless - - - ERPathway2016; ER Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=12573; RecordID=ERPathway2016_35; DatasetName=ERPathway2016; DTXSID=DTXSID3021645; Assay=ER Pathway Model, Antagonist; Endpoint=Model Score; Response=0.0142; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation 91 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_skin_irritation Breakthrough Time 240 min - Dermal - In Vitro; Corrositex sheet=Data_invitro; excel_row=2285; Record_ID=skin_irritation_invitro_63; Data_Type=In Vitro; Formulation_ID=MIX783; Formulation_Name=Capric/caprylic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=Corrositex; Endpoint=Breakthrough Time; Response=240; Response_Unit=min; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation GHS classification 1 unitless Rabbit Dermal - In Vivo; Draize Skin Irritation/Corrosion Test sheet=Data_invivo; excel_row=722; Record_ID=skin_irritation_invivo_124; Data_Type=In Vivo; Concentration=95; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=Draize Skin Irritation/Corrosion Test; Endpoint=GHS classification; Response=1B; Response_Unit=Unitless; Species=Rabbit; Reference=ICCVAM 2002; Not available; https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Positive reaction 76.2 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=721; Record_ID=skin_irritation_invivo_58; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=76.2; Response_Unit=%; Species=Human; Reference=Basketter et al. 2004; 15291823; 10.1111/j.0105-1873.2004.00385.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 1.6 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2445; Record_ID=skin_irritation_invitro_2538; Data_Type=In Vitro; Formulation_ID=MIX783; Formulation_Name=Capric/caprylic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=1.6; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 3.8 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2446; Record_ID=skin_irritation_invitro_2539; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=3.8; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 10.4 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2447; Record_ID=skin_irritation_invitro_2491; Data_Type=In Vitro; Formulation_ID=MIX783; Formulation_Name=Capric/caprylic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=10.4; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 13.4 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2448; Record_ID=skin_irritation_invitro_2492; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=13.4; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 10.6 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2449; Record_ID=skin_irritation_invitro_2513; Data_Type=In Vitro; Formulation_ID=MIX794; Formulation_Name=Oleic/caprylic acid; Percent_Active_Ingredient=20; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=10.6; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation TER 18.5 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=2450; Record_ID=skin_irritation_invitro_2514; Data_Type=In Vitro; Formulation_ID=MIX794; Formulation_Name=Oleic/caprylic acid; Percent_Active_Ingredient=20; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=TER Corrosion; Endpoint=TER; Response=18.5; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 3 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2426; Record_ID=skin_irritation_invitro_1835; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=3; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2427; Record_ID=skin_irritation_invitro_1839; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 3.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2428; Record_ID=skin_irritation_invitro_1844; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=3.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 7.3 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2429; Record_ID=skin_irritation_invitro_1816; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=7.3; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 4.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2431; Record_ID=skin_irritation_invitro_1833; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=4.60; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 2.7 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2433; Record_ID=skin_irritation_invitro_1836; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=2.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 3.5 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2434; Record_ID=skin_irritation_invitro_1838; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=3.5; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (240 minutes) 5.3 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2435; Record_ID=skin_irritation_invitro_2169; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=5.3; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 77.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2345; Record_ID=skin_irritation_invitro_1839; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=77.40; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 55 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2346; Record_ID=skin_irritation_invitro_1844; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=55; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 103.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2347; Record_ID=skin_irritation_invitro_1816; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=103.6; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 51.4 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2348; Record_ID=skin_irritation_invitro_1819; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=51.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 48.7 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2349; Record_ID=skin_irritation_invitro_1823; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=48.7; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 52.6 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2350; Record_ID=skin_irritation_invitro_1826; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=52.6; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 55.4 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2351; Record_ID=skin_irritation_invitro_1829; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=55.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 73 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2352; Record_ID=skin_irritation_invitro_1832; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=73; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 62.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2353; Record_ID=skin_irritation_invitro_1834; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=62.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 84.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2354; Record_ID=skin_irritation_invitro_1836; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=84.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 100.7 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2355; Record_ID=skin_irritation_invitro_1838; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=100.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 59.3 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2356; Record_ID=skin_irritation_invitro_1831; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=59.3; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 68.8 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2357; Record_ID=skin_irritation_invitro_1833; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=68.8; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 103.2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2358; Record_ID=skin_irritation_invitro_1835; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=103.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 38.4 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2359; Record_ID=skin_irritation_invitro_1837; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=38.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 16.9 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2360; Record_ID=skin_irritation_invitro_2136; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=16.90; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 46.3 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2361; Record_ID=skin_irritation_invitro_2138; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=46.3; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 20.5 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2362; Record_ID=skin_irritation_invitro_2140; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=20.5; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 53.9 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2363; Record_ID=skin_irritation_invitro_2142; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=53.9; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 73.9 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2364; Record_ID=skin_irritation_invitro_2144; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=73.90; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 63.1 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2365; Record_ID=skin_irritation_invitro_2146; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=63.1; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 41.3 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2366; Record_ID=skin_irritation_invitro_2148; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=41.3; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 35.4 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2367; Record_ID=skin_irritation_invitro_2150; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=35.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 24.2 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2368; Record_ID=skin_irritation_invitro_2152; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=24.2; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 27.4 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2369; Record_ID=skin_irritation_invitro_2154; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=27.4; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 51.6 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2370; Record_ID=skin_irritation_invitro_2156; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=51.6; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 30.5 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2371; Record_ID=skin_irritation_invitro_2158; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=30.5; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 12.2 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2372; Record_ID=skin_irritation_invitro_2160; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=12.2; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 78.7 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2373; Record_ID=skin_irritation_invitro_2162; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=78.7; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 90.4 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2374; Record_ID=skin_irritation_invitro_2164; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=90.4; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 81.8 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2375; Record_ID=skin_irritation_invitro_2166; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=81.8; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 24.8 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2376; Record_ID=skin_irritation_invitro_2168; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=24.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 16.5 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2377; Record_ID=skin_irritation_invitro_2169; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=16.5; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 25 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2378; Record_ID=skin_irritation_invitro_2171; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=25; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 18.2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2379; Record_ID=skin_irritation_invitro_2173; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=18.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 25.4 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2380; Record_ID=skin_irritation_invitro_2175; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=25.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 29.5 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2381; Record_ID=skin_irritation_invitro_2177; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=29.5; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 31.7 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2382; Record_ID=skin_irritation_invitro_2179; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=31.7; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 68.6 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2383; Record_ID=skin_irritation_invitro_2181; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=68.60; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 49.1 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2384; Record_ID=skin_irritation_invitro_2183; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=49.1; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (3 minutes) 61.2 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2385; Record_ID=skin_irritation_invitro_2186; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=61.2; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 18 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2386; Record_ID=skin_irritation_invitro_1831; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=18; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 13.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2387; Record_ID=skin_irritation_invitro_1833; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=13.6; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 7.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2388; Record_ID=skin_irritation_invitro_1835; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=7.6; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 10.1 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2389; Record_ID=skin_irritation_invitro_1837; Data_Type=In Vitro; Formulation_ID=MIX819; Formulation_Name=55/45 Octanoic/decanoic acid; Percent_Active_Ingredient=55; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=10.1; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 7.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2390; Record_ID=skin_irritation_invitro_1839; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=7.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 12.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2391; Record_ID=skin_irritation_invitro_1844; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=12.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 9.5 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2393; Record_ID=skin_irritation_invitro_1819; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=9.5; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 11.4 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2394; Record_ID=skin_irritation_invitro_1823; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=11.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 8.5 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2395; Record_ID=skin_irritation_invitro_1838; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=8.5; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 8.8 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2397; Record_ID=skin_irritation_invitro_1829; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=8.80; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 8 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2398; Record_ID=skin_irritation_invitro_1832; Data_Type=In Vitro; Formulation_ID=MIX818; Formulation_Name=60/40 Octanoic/decanoic acid; Percent_Active_Ingredient=60; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=8; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 8.9 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2399; Record_ID=skin_irritation_invitro_1834; Data_Type=In Vitro; Formulation_ID=MIX820; Formulation_Name=65/35 Octanoic/decanoic acid; Percent_Active_Ingredient=65; Mixture=Mixture; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=8.9; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2401; Record_ID=skin_irritation_invitro_2142; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2.5 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2402; Record_ID=skin_irritation_invitro_2144; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2.5; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2.7 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2403; Record_ID=skin_irritation_invitro_2146; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2.7; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 1.8 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2404; Record_ID=skin_irritation_invitro_2148; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=1.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 1.6 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2405; Record_ID=skin_irritation_invitro_2150; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=1.6; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 3.4 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2406; Record_ID=skin_irritation_invitro_2152; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=3.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2.1 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2408; Record_ID=skin_irritation_invitro_2156; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2.1; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 1.7 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2409; Record_ID=skin_irritation_invitro_2158; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=1.7; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 0.5 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2411; Record_ID=skin_irritation_invitro_2162; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=0.5; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 0.7 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2412; Record_ID=skin_irritation_invitro_2164; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=0.7; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 0.3 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=2413; Record_ID=skin_irritation_invitro_2166; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=0.3; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 6.5 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2414; Record_ID=skin_irritation_invitro_2168; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=6.5; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 3.3 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2415; Record_ID=skin_irritation_invitro_2136; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=3.3; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 4.1 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2416; Record_ID=skin_irritation_invitro_2169; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=4.10; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2.6 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2417; Record_ID=skin_irritation_invitro_2138; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2.6; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 6.7 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2418; Record_ID=skin_irritation_invitro_2171; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=6.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 2.2 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=2419; Record_ID=skin_irritation_invitro_2140; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=2.20; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 3.7 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2420; Record_ID=skin_irritation_invitro_2173; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=3.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 8.1 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2421; Record_ID=skin_irritation_invitro_2177; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=8.1; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 5.3 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2422; Record_ID=skin_irritation_invitro_2179; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=5.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_irritation Viability (60 minutes) 7.3 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=2424; Record_ID=skin_irritation_invitro_2183; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=7.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization 15 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_skin_sensitization CD54, EC200 158.7 ug/mL - Dermal - In Vitro; CE_hCLAT2018; h-CLAT sheet=Data_invitro; excel_row=2267; Record_ID=skin_sensitization_invitro_556; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=158.69999999999999; Reported_Response_Unit=ug/mL; Response=158.7; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization CD86, EC150 5.408 ug/mL - Dermal - In Vitro; Urbisch_SkinSensitization2020; U-SENS sheet=Data_invitro; excel_row=8153; Record_ID=skin_sensitization_invitro_2176; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=37.5; Reported_Response_Unit=uM; Conversion_Factor_Value=144.214; Conversion_Factor_Source=EPA Dashboard; Converted_Response=5.408; Converted_Response_Unit=ug/mL; Response=5.408; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization CD86, EC150 70.49 ug/mL - Dermal - In Vitro; CE_USENSE2018; U-SENS sheet=Data_invitro; excel_row=8750; Record_ID=skin_sensitization_invitro_2424; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=70.49; Reported_Response_Unit=ug/mL; Response=70.49; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization CV70 >200 ug/mL - Dermal - In Vitro; CE_USENSE2018; U-SENS sheet=Data_invitro; excel_row=8745; Record_ID=skin_sensitization_invitro_2424; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=U-SENS; Endpoint=CV70; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=200; Reported_Response_Unit=ug/mL; Response=200; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization CV75 359 ug/mL - Dermal - In Vitro; CE_hCLAT2018; h-CLAT sheet=Data_invitro; excel_row=2268; Record_ID=skin_sensitization_invitro_556; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=h-CLAT; Endpoint=CV75; Reported_Response=359; Reported_Response_Unit=ug/mL; Response=359; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Depletion Cys 1.9 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=886; Record_ID=skin_sensitization_invitro_245; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=1.9; Reported_Response_Unit=%; Response=1.9; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Depletion Cys -1 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=890; Record_ID=skin_sensitization_invitro_246; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=-1; Reported_Response_Unit=%; Response=-1; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Jaworska 2011; 23670904; 10.1002/jat.2869|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Depletion Lys 1.8 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=885; Record_ID=skin_sensitization_invitro_245; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=1.8; Reported_Response_Unit=%; Response=1.8; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Depletion Lys 0.9 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=889; Record_ID=skin_sensitization_invitro_246; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=0.9; Reported_Response_Unit=%; Response=0.9; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Jaworska 2011; 23670904; 10.1002/jat.2869|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Depletion Lys + Cys 0.45 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=891; Record_ID=skin_sensitization_invitro_246; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=0.45; Reported_Response_Unit=%; Response=0.45; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Jaworska 2011; 23670904; 10.1002/jat.2869|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization EC1.5 >2000 uM - Dermal - In Vitro; CE_KeratinoSense2018; KeratinoSens sheet=Data_invitro; excel_row=4979; Record_ID=skin_sensitization_invitro_1153; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=KeratinoSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2000; Reported_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Imax 1.1 ratio - Dermal - In Vitro; CE_KeratinoSense2018; KeratinoSens sheet=Data_invitro; excel_row=4982; Record_ID=skin_sensitization_invitro_1153; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.1000000000000001; Reported_Response_Unit=Unitless; Response=1.1; Response_Unit=Ratio; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Incidence of positive responses 0 % Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=4587; Record_ID=skin_sensitization_invivo_1102; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=1.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=Human Maximization Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Kligman 1977: report to RIFM|Opdyke 1981; Not available; 10.1016/0015-6264(81)90363-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Induction dose per skin area 675 ug/cm2 Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=4585; Record_ID=skin_sensitization_invivo_1102; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=1.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=675; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Kligman 1977: report to RIFM|Opdyke 1981; Not available; 10.1016/0015-6264(81)90363-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
NTP_ICE_skin_sensitization Relative reliability score 3 unitless Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=4591; Record_ID=skin_sensitization_invivo_1102; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=1.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID3021645; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=3; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Kligman 1977: report to RIFM|Opdyke 1981; Not available; 10.1016/0015-6264(81)90363-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021645; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID3021645
ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =2700 mg/kg bw/day Rat oral - developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac56e4b0a7c65d1bea12; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/27581/7/9/3?documentUUID=9b237a1e-f974-4bf1-9ced-a41a73924131; YEAR=1979; ORIGINAL_YEAR=1979; STUDY_GROUP=ECHA IUCLID:15821500:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0826ec5562ec9d969d9fad622df91710
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaebde4b0a7c65d1cab2a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/27581/7/6/2?documentUUID=9b237a1e-f974-4bf1-9ced-a41a73924131; YEAR=1979; ORIGINAL_YEAR=1979; STUDY_GROUP=ECHA IUCLID:15838812:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_40bcfe87e5d57f030c8ca015c9d1c3d1
ToxValDB_ECOTOX 7 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECOTOX LOEL =0.5 mmol Rat injection acute; 0.0208 days acute LONG_REF=J. Hepatol.4(1): 118-126 Jones,D.B., K.D. Mullen, M. Roessle, T. Maynard, and E.A. Jones Hepatic Encephalopathy. Application of Visual Evoked Responses to Test Hypotheses of Its Pathogenesis in Rats 1987; TITLE=Hepatic Encephalopathy. Application of Visual Evoked Responses to Test Hypotheses of Its Pathogenesis in Rats; AUTHOR=Jones,D.B., K.D. Mullen, M. Roessle, T. Maynard, and E.A. Jones; DOI=10.1016/s0168-8278(87)80018-1; QUALITY=Control type: Multiple control types; EXTERNAL_SOURCE_ID=105492; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1987; ORIGINAL_YEAR=1987; TOXICOLOGICAL_EFFECT=Physiology: Electroencephalogram; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECOTOX:15595663:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=96cda5c5b85a4cf6bab8efee30f637cc
ToxValDB_ECOTOX LOEL =2.3 mg/mi Rat injection acute; 0.0625 days acute LONG_REF=Physiol. Behav.87(2): 388-395 Jambor de Sousa,U.L., M. Arnold, W. Langhans, N. Geary, and M. Leonhardt Caprylic Acid Infusion Acts in the Liver to Decrease Food Intake in Rats 2006; TITLE=Caprylic Acid Infusion Acts in the Liver to Decrease Food Intake in Rats; AUTHOR=Jambor de Sousa,U.L., M. Arnold, W. Langhans, N. Geary, and M. Leonhardt; DOI=10.1016/j.physbeh.2005.11.004; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=103576; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2006; ORIGINAL_YEAR=2006; TOXICOLOGICAL_EFFECT=Physiology: Clearance; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15598406:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=fc0e4ed3b86e21a899898615374f1565
ToxValDB_ECOTOX LOEL =1 % Rat oral short-term; 2 days short-term LONG_REF=Physiol. Behav.66(2): 285-288 Tsuruta,M., T. Kawada, T. Fukuwatari, and T. Fushiki The Orosensory Recognition of Long-Chain Fatty Acids in Rats 1999; TITLE=The Orosensory Recognition of Long-Chain Fatty Acids in Rats; AUTHOR=Tsuruta,M., T. Kawada, T. Fukuwatari, and T. Fushiki; DOI=10.1016/s0031-9384(98)00299-6; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=103402; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1999; ORIGINAL_YEAR=1999; TOXICOLOGICAL_EFFECT=Avoidance: Water avoidance; TOXICOLOGICAL_EFFECT_CATEGORY=food and/or water consumption; STUDY_GROUP=ECOTOX:15603923:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=04f11b29789ece4fa78e02e0490481ea
ToxValDB_ECOTOX LOEL =15 mmol/kg Mouse injection acute; 0.0021 days acute LONG_REF=Brain Res.335(1): 131-137 McCandless,D.W. Octanoic Acid-Induced Coma and Reticular Formation Energy Metabolism 1985; TITLE=Octanoic Acid-Induced Coma and Reticular Formation Energy Metabolism; AUTHOR=McCandless,D.W.; DOI=10.1016/0006-8993(85)90283-5; QUALITY=Control type: Multiple control types; EXTERNAL_SOURCE_ID=105149; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=Biochemistry: Glucose; TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry; STUDY_GROUP=ECOTOX:15607489:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=48d47f8a7570aab2c4d47014a088c6bf
ToxValDB_ECOTOX LOEL =2 mmol Rat injection acute; 36 hours short-term LONG_REF=J. Lab. Clin. Med.106(5): 583-588 Zieve,L., R. Dozeman, D. LaFontaine, and K. Draves Effect of Hepatic Failure Toxins on Liver Thymidine Kinase Activity and Ornithine Decarboxylase Activity After Massive Necrosis with Acetaminophen in the Rat 1985; TITLE=Effect of Hepatic Failure Toxins on Liver Thymidine Kinase Activity and Ornithine Decarboxylase Activity After Massive Necrosis with Acetaminophen in the Rat; AUTHOR=Zieve,L., R. Dozeman, D. LaFontaine, and K. Draves; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=99159; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=Enzyme(s): Thymidine kinase; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity; STUDY_GROUP=ECOTOX:15611551:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=16c320de72acf6aaafced246f8a1981f
ToxValDB_ECOTOX NOEL =350 mM Rat injection acute; 0.0625 days acute LONG_REF=Physiol. Behav.87(2): 388-395 Jambor de Sousa,U.L., M. Arnold, W. Langhans, N. Geary, and M. Leonhardt Caprylic Acid Infusion Acts in the Liver to Decrease Food Intake in Rats 2006; TITLE=Caprylic Acid Infusion Acts in the Liver to Decrease Food Intake in Rats; AUTHOR=Jambor de Sousa,U.L., M. Arnold, W. Langhans, N. Geary, and M. Leonhardt; DOI=10.1016/j.physbeh.2005.11.004; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=103576; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2006; ORIGINAL_YEAR=2006; TOXICOLOGICAL_EFFECT=Hormone(s): Corticosterone (Corticoid); TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry; STUDY_GROUP=ECOTOX_dup_EPA ORD_15595836_15604159:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=662f7c430018b033552a30afa200e8b1
ToxValDB_ECOTOX NOEL =5000 ppm European Rabbit oral short-term; 18 days short-term LONG_REF=Vet. Microbiol.126(4): 372-376 Skrivanova,E., Z. Molatova, and M. Marounek Effects of Caprylic Acid and Triacylglycerols of Both Caprylic and Capric Acid in Rabbits Experimentally Infected with Enteropathogenic Escherichia coli O103 2008; TITLE=Effects of Caprylic Acid and Triacylglycerols of Both Caprylic and Capric Acid in Rabbits Experimentally Infected with Enteropathogenic Escherichia coli O103; AUTHOR=Skrivanova,E., Z. Molatova, and M. Marounek; DOI=10.1016/j.vetmic.2007.07.010; QUALITY=Control type: Multiple control types; EXTERNAL_SOURCE_ID=103502; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2008; ORIGINAL_YEAR=2008; TOXICOLOGICAL_EFFECT=Mortality: Mortality; TOXICOLOGICAL_EFFECT_CATEGORY=mortality/survival; STUDY_GROUP=ECOTOX_dup_EPA ORD_15596321_15599697:M/F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=506e9a85e0741327a7bd2df88a059f24
ToxValDB_HESS 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_HESS NOEL <62.5 mg/kg bw/day Rat oral - subchronic STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/60da0ddae4b0a676289ddea5; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.nite.go.jp/en/chem/qsar/hess_update-e.html; TOXICOLOGICAL_EFFECT=Blood Chemistry: IP increase|Thyroid Hormone: Thyroid hormones', 'N/A|Necropsy: Stomach-Thickening, forestomach|Histopathology: Stomach-Hyperplasia, squamous epithelium, forestomach Stomach-Ulcer, forestomach; TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry|gross pathology|nonneoplastic histopathology; STUDY_GROUP=HESS_dup_-_15638631_15638632:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_dcf9322b9b842f56c47b9fcbad9411c2
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier OBL58JN025 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H16O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"OBL58JN025"}
openFDA substances FDA UNII substance identifier OBL58JN025 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H16O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"OBL58JN025"}
openFDA substances FDA UNII substance identifier OBL58JN025 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H16O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"OBL58JN025"}
openFDA substances FDA UNII substance identifier OBL58JN025 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H16O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"OBL58JN025"}