Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Enzyme activity may cause irritation at high concentrations with potential for protein-based sensitization.
Regulatory Flags
Frequently Asked Questions
Is Carboxylesterase safe in cosmetics?
Enzyme activity may cause irritation at high concentrations with potential for protein-based sensitization. The EU classifies Carboxylesterase as "permitted". Safety rating: MODERATE.
Is Carboxylesterase allowed in the EU?
Carboxylesterase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Carboxylesterase do in cosmetics?
Carboxylesterase functions as: Skin conditioning enzyme that catalyzes hydrolysis of carboxylic esters. It is classified as a cosmetic ingredient in our database. CAS number: 9016-18-6 (general enzyme CAS).
What is the Margin of Safety for Carboxylesterase?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Carboxylesterase compliance across multiple jurisdictions:
Related Ingredients
Is Carboxylesterase in Your Products?
Scan any product label with Piro โ our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free โAnalyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Carboxylesterase in your formulation.