Regulatory Status
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Safety Data
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Expert Verdict
Cassia fistula stem bark extract is a traditional Ayurvedic botanical with well-documented antioxidant, antimicrobial and anti-aging bioactivity. The extract shows strong radical scavenging (IC50 8–19 µg/mL), tyrosinase inhibition, and skin barrier-enhancing properties. Listed in EU CosIng as a skin conditioning ingredient with no Annex II or Annex III classification. Not on FDA prohibited or restricted list. Anthraquinone constituents (rhein, chrysophanol) are weakly genotoxic in vitro at high doses, but at cosmetic use concentrations via topical route this risk is low and manageable. Overall safety profile is good for use as a skin-conditioning, antioxidant active in rinse-off and leave-on products at typical concentrations up to 2–5%.
Regulatory Flags
Frequently Asked Questions
Is Cassia Fistula Stem Bark Extract safe in cosmetics?
Cassia fistula stem bark extract is a traditional Ayurvedic botanical with well-documented antioxidant, antimicrobial and anti-aging bioactivity. The extract shows strong radical scavenging (IC50 8–19 µg/mL), tyrosinase inhibition, and skin barrier-enhancing properties. Listed in EU CosIng as a skin conditioning ingredient with no Annex II or Annex III classification. Not on FDA prohibited or restricted list. Anthraquinone constituents (rhein, chrysophanol) are weakly genotoxic in vitro at high doses, but at cosmetic use concentrations via topical route this risk is low and manageable. Overall safety profile is good for use as a skin-conditioning, antioxidant active in rinse-off and leave-on products at typical concentrations up to 2–5%. The EU classifies Cassia Fistula Stem Bark Extract as "permitted". Safety rating: GOOD.
Is Cassia Fistula Stem Bark Extract allowed in the EU?
Cassia Fistula Stem Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cassia Fistula Stem Bark Extract do in cosmetics?
Cassia Fistula Stem Bark Extract functions as: Skin conditioning agent; antioxidant; tyrosinase inhibitor with anti-aging, antimicrobial and anti-inflammatory properties derived from the stem bark of Cassia fistula (Golden Shower tree), Leguminosae/Fabaceae family. It is classified as a cosmetic ingredient in our database. CAS number: 84848-75-9.
What is the Margin of Safety for Cassia Fistula Stem Bark Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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