Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for cis-2-Methyl-4-propyl-1,3-oxathiane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=600 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
FEMA GRAS fragrance ingredient with sulfur-containing structure; safety assessment based on RIFM evaluation and read-across data from structural analogs.
Regulatory Flags
Frequently Asked Questions
Is cis-2-Methyl-4-propyl-1,3-oxathiane safe in cosmetics?
FEMA GRAS fragrance ingredient with sulfur-containing structure; safety assessment based on RIFM evaluation and read-across data from structural analogs. The EU classifies cis-2-Methyl-4-propyl-1,3-oxathiane as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is cis-2-Methyl-4-propyl-1,3-oxathiane allowed in the EU?
cis-2-Methyl-4-propyl-1,3-oxathiane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does cis-2-Methyl-4-propyl-1,3-oxathiane do in cosmetics?
cis-2-Methyl-4-propyl-1,3-oxathiane functions as: Fragrance with galbanum, green, and sulfurous notes. It is classified as a cosmetic ingredient in our database. CAS number: 59323-76-1.
What is the Margin of Safety for cis-2-Methyl-4-propyl-1,3-oxathiane?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for cis-2-Methyl-4-propyl-1,3-oxathiane?
The NOAEL (No Observed Adverse Effect Level) for cis-2-Methyl-4-propyl-1,3-oxathiane is >=600 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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