Citrus Aurantifolia Seed Oil Unsaponifiables
INCI: CITRUS AURANTIFOLIA SEED OIL UNSAPONIFIABLES
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Citrus Aurantifolia Seed Oil Unsaponifiables. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 181 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 304 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 304 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 8500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| dose_tested | 181 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| dose_tested | 304 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| dose_tested | 8500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
Expert Verdict
Very limited published safety data specific to this ingredient; characterization of sterol and tocopherol content recommended along with heavy metal and pesticide residue testing.
Regulatory Flags
Frequently Asked Questions
Is Citrus Aurantifolia Seed Oil Unsaponifiables safe in cosmetics?
Very limited published safety data specific to this ingredient; characterization of sterol and tocopherol content recommended along with heavy metal and pesticide residue testing. The EU classifies Citrus Aurantifolia Seed Oil Unsaponifiables as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.
Is Citrus Aurantifolia Seed Oil Unsaponifiables allowed in the EU?
Citrus Aurantifolia Seed Oil Unsaponifiables EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citrus Aurantifolia Seed Oil Unsaponifiables do in cosmetics?
Citrus Aurantifolia Seed Oil Unsaponifiables functions as: Skin-conditioning agent, emollient, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 8008-26-2.
What is the Margin of Safety for Citrus Aurantifolia Seed Oil Unsaponifiables?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Citrus Aurantifolia Seed Oil Unsaponifiables?
The NOAEL (No Observed Adverse Effect Level) for Citrus Aurantifolia Seed Oil Unsaponifiables is 181 mg/kg bw/day based on a Chronic study via oral route in mouse. A total of 7 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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