Clematis Alpina Callus Extract

INCI: CLEMATIS ALPINA CALLUS EXTRACT

CAS Number
Not assigned (plant cell culture-derived extract)
Function
Antioxidant, skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no prohibition; manufacturer must substantiate safety

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published toxicological data; as a callus (plant stem-cell) extract, it is produced under controlled conditions reducing wild-harvest variability; potential allergenicity from Ranunculaceae-family compounds (protoanemonin) should be assessed. Derived from dedifferentiated plant cells of Clematis alpina (Alpine clematis); callus culture technology provides a standardized, sustainable supply of bioactive compounds with antioxidant and protective activity

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen natural-origin

Frequently Asked Questions

Is Clematis Alpina Callus Extract safe in cosmetics?

Limited published toxicological data; as a callus (plant stem-cell) extract, it is produced under controlled conditions reducing wild-harvest variability; potential allergenicity from Ranunculaceae-family compounds (protoanemonin) should be assessed. Derived from dedifferentiated plant cells of Clematis alpina (Alpine clematis); callus culture technology provides a standardized, sustainable supply of bioactive compounds with antioxidant and protective activity The EU classifies Clematis Alpina Callus Extract as "permitted". Safety rating: MODERATE.

Is Clematis Alpina Callus Extract allowed in the EU?

Clematis Alpina Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Clematis Alpina Callus Extract do in cosmetics?

Clematis Alpina Callus Extract functions as: Antioxidant, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (plant cell culture-derived extract).

What is the Margin of Safety for Clematis Alpina Callus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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