Cleome Gynandra Leaf Extract

INCI: CLEOME GYNANDRA LEAF EXTRACT

CAS Number
Not assigned (botanical extract; no unique CAS in CosIng)
Function
Anti-sebum, skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically reviewed by FDA or CIR; no restrictions; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Commercially available as Pixalia® (Laboratoires Expanscience), an eco-designed active ingredient sourced from Burkina Faso with established supply chain documentation. Relatively well-characterized compared to other ingredients in this category. Recommend requesting supplier's complete safety dossier including HRIPT data.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Cleome Gynandra Leaf Extract safe in cosmetics?

Commercially available as Pixalia® (Laboratoires Expanscience), an eco-designed active ingredient sourced from Burkina Faso with established supply chain documentation. Relatively well-characterized compared to other ingredients in this category. Recommend requesting supplier's complete safety dossier including HRIPT data. The EU classifies Cleome Gynandra Leaf Extract as "permitted". Safety rating: GOOD.

Is Cleome Gynandra Leaf Extract allowed in the EU?

Cleome Gynandra Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cleome Gynandra Leaf Extract do in cosmetics?

Cleome Gynandra Leaf Extract functions as: Anti-sebum, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (botanical extract; no unique CAS in CosIng).

What is the Margin of Safety for Cleome Gynandra Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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