Moderate Cosmetic Ingredient

Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate)

INCI: COCAMIDE DEA SESQUI(COCOYL METHYL BETA-ALANINATE)

CAS Number
Not individually assigned (INCI glossary entry only; mixture of mono-/diesters of Cocamide DEA [CAS 68603-42-9] and Cocoyl Methyl Beta-Alanine)
Function
Humectant, skin conditioning (emollient), surfactant–cleansing, surfactant–emulsifying
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes FDA: no specific restriction. CIR assessed the parent Cocamide DEA as safe in rinse-off products and ≤10% in leave-on products, provided no nitrosating agents are present. California Proposition 65 lists Cocamide DEA as known carcinogen (June 2012)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

IARC 2B carcinogen (DEA moiety); nitrosamine formation risk if compounded with nitrosating agents; California Prop 65 listing; no standalone CIR or SCCS opinion on this specific INCI

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Concern Level: High

Frequently Asked Questions

Is Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) safe in cosmetics?

IARC 2B carcinogen (DEA moiety); nitrosamine formation risk if compounded with nitrosating agents; California Prop 65 listing; no standalone CIR or SCCS opinion on this specific INCI The EU classifies Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) as "restricted". Safety rating: MODERATE.

Is Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) allowed in the EU?

Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) do in cosmetics?

Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) functions as: Humectant, skin conditioning (emollient), surfactant–cleansing, surfactant–emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (INCI glossary entry only; mixture of mono-/diesters of Cocamide DEA [CAS 68603-42-9] and Cocoyl Methyl Beta-Alanine).

What is the Margin of Safety for Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Cocamide DEA Sesqui(Cocoyl Methyl Beta-Alaninate) compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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