Also known as: N,N-Dimethyl-N-(3-(coconut oil alkyl)amidopropyl)amine oxide, EINECS 268-938-5, N-(3-(Dimethylamino)propyl) coco amides N-oxides, UNII-M4SL82J7HK
INCI: COCAMIDOPROPYLAMINE OXIDE
Cocamidopropylamine Oxide (CAS 68155-09-9) is a cosmetic cosmetic ingredient functioning as Surfactant (cleansing), surfactant (foam boosting), surfactant (hydrotrope),. NOAEL 50 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted; 4 safety opinions reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68155-09-9 →
Cocamidopropylamine Oxide is classified GHS Danger (H302, H315, H318, H373, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Cocamidopropylamine Oxide.
Calculate MoS for your specific formulation with the MoS Calculator.
1 study endpoint found for Cocamidopropylamine Oxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | short-term | ECHA |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Pre-calculated NOAEL → SED → MoS audit trail for Cocamidopropylamine Oxide across SCCS product categories, with measured dermal absorption where available.
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Preliminary editorial summary for Cocamidopropylamine Oxide — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Cocamidopropylamine Oxide by CAS number or substance name.
Cocamidopropylamine Oxide has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by CIR Safety Assessment.
Cocamidopropylamine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Cocamidopropylamine Oxide functions as: Surfactant (cleansing), surfactant (foam boosting), surfactant (hydrotrope), hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68155-09-9.
The NOAEL (No Observed Adverse Effect Level) for Cocamidopropylamine Oxide is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ECHA.
Cocamidopropylamine Oxide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Cocamidopropylamine Oxide is classified GHS Danger (H302, H315, H318, H373, H411) in the chemicals database but is allowed in EU cosmetics.
Check Cocamidopropylamine Oxide compliance across multiple jurisdictions:
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