Cocamidopropyltrimonium Chloride

INCI: COCAMIDOPROPYLTRIMONIUM CHLORIDE

CAS Number
Not discretely assigned (coco-derived quaternary mixture); structurally related to CAS 71850-81-2
Function
Antistatic agent, hair conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted for cosmetic use; no specific restrictions; consistent with CIR quaternary ammonium group assessments

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cationic surfactant with potential eye irritant properties at high concentrations; formulate to be non-irritating and apply standard quaternary ammonium safety precautions.

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Concern Level: Moderate

Frequently Asked Questions

Is Cocamidopropyltrimonium Chloride safe in cosmetics?

Cationic surfactant with potential eye irritant properties at high concentrations; formulate to be non-irritating and apply standard quaternary ammonium safety precautions. The EU classifies Cocamidopropyltrimonium Chloride as "restricted". Safety rating: GOOD.

Is Cocamidopropyltrimonium Chloride allowed in the EU?

Cocamidopropyltrimonium Chloride EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocamidopropyltrimonium Chloride do in cosmetics?

Cocamidopropyltrimonium Chloride functions as: Antistatic agent, hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not discretely assigned (coco-derived quaternary mixture); structurally related to CAS 71850-81-2.

What is the Margin of Safety for Cocamidopropyltrimonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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