Coco-Hydroxysultaine

INCI: COCO-HYDROXYSULTAINE

CAS Number
Related to group CAS 68139-30-0 (Cocamidopropyl Hydroxysultaine is the most-reviewed analog)
Function
Antistatic, foam boosting, surfactant, cleansing, foam stabilizing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed 13 alkyl sultaines (2024) โ€” Expert Panel concluded safe in present practices of use and concentration. Cocamidopropyl Hydroxysultaine used in 310 formulations per VCRP

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Serious eye irritation potential flagged by NICNAS assessment โ€” up to 5% in leave-on and up to 10% in rinse-off per NICNAS guidance. Ensure adequate rinsing in eye-area products. Minor impurity concerns (residual 3-dimethylaminopropylamine/DMAPA) typical of amidoamine-derived surfactants.

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Concern Level: Moderate

Frequently Asked Questions

Is Coco-Hydroxysultaine safe in cosmetics?

Serious eye irritation potential flagged by NICNAS assessment โ€” up to 5% in leave-on and up to 10% in rinse-off per NICNAS guidance. Ensure adequate rinsing in eye-area products. Minor impurity concerns (residual 3-dimethylaminopropylamine/DMAPA) typical of amidoamine-derived surfactants. The EU classifies Coco-Hydroxysultaine as "permitted". Safety rating: GOOD.

Is Coco-Hydroxysultaine allowed in the EU?

Coco-Hydroxysultaine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coco-Hydroxysultaine do in cosmetics?

Coco-Hydroxysultaine functions as: Antistatic, foam boosting, surfactant, cleansing, foam stabilizing. It is classified as a cosmetic ingredient in our database. CAS number: Related to group CAS 68139-30-0 (Cocamidopropyl Hydroxysultaine is the most-reviewed analog).

What is the Margin of Safety for Coco-Hydroxysultaine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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