Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Coffea Arabica Seed Powder. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 33 mg/kg bw/day | oral | mouse | Special Toxicology Study | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1483 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1716 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 1958 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1931 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 2489 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 3750 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 3725 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 3775 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
Expert Verdict
Particle size distribution critical โ sharp or irregular particles may cause micro-tears; must control for microbial contamination (natural plant material, Aw); not a microplastic alternative concern
Regulatory Flags
Frequently Asked Questions
Is Coffea Arabica Seed Powder safe in cosmetics?
Particle size distribution critical โ sharp or irregular particles may cause micro-tears; must control for microbial contamination (natural plant material, Aw); not a microplastic alternative concern The EU classifies Coffea Arabica Seed Powder as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Coffea Arabica Seed Powder allowed in the EU?
Coffea Arabica Seed Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coffea Arabica Seed Powder do in cosmetics?
Coffea Arabica Seed Powder functions as: Abrasive, Skin Conditioning, Masking. It is classified as a cosmetic ingredient in our database. CAS number: 84650-00-0.
What is the Margin of Safety for Coffea Arabica Seed Powder?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Coffea Arabica Seed Powder?
The NOAEL (No Observed Adverse Effect Level) for Coffea Arabica Seed Powder is 33 mg/kg bw/day based on a Special Toxicology Study study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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