Coffea Arabica Seedcake Extract
INCI: COFFEA ARABICA SEEDCAKE EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Coffea Arabica Seedcake Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 33 mg/kg bw/day | oral | mouse | Special Toxicology Study | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1483 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1716 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 1958 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1931 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 2489 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 3750 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 3725 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 3775 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
Expert Verdict
Upcycled/byproduct ingredient with good safety profile; extraction solvent residues and microbial load must be controlled due to batch-to-batch variability from source material.
Regulatory Flags
Frequently Asked Questions
Is Coffea Arabica Seedcake Extract safe in cosmetics?
Upcycled/byproduct ingredient with good safety profile; extraction solvent residues and microbial load must be controlled due to batch-to-batch variability from source material. The EU classifies Coffea Arabica Seedcake Extract as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Coffea Arabica Seedcake Extract allowed in the EU?
Coffea Arabica Seedcake Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coffea Arabica Seedcake Extract do in cosmetics?
Coffea Arabica Seedcake Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84650-00-0.
What is the Margin of Safety for Coffea Arabica Seedcake Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Coffea Arabica Seedcake Extract?
The NOAEL (No Observed Adverse Effect Level) for Coffea Arabica Seedcake Extract is 33 mg/kg bw/day based on a Special Toxicology Study study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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