Coprosma Grandifolia Leaf/Stem Extract

INCI: COPROSMA GRANDIFOLIA LEAF/STEM EXTRACT

CAS Number
Not assigned (rare botanical extract)
Function
Skin conditioning; traditional Māori medicine for skin diseases, stomach aches, wounds
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA not specifically restricting. No CIR monograph. Minimal US market presence.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap identified. New Zealand endemic species (Rubiaceae family) with yellow/orange dye in inner bark; potential staining and colorant concerns. No published dermal toxicity, sensitization, or irritation data available. Requires full toxicological dossier including acute dermal toxicity, irritation, sensitization, and genotoxicity studies before CPSR acceptance. Extraction solvent, standardization, and botanical authentication must be specified.

⚠️
Concern Level: High

Regulatory Flags

plant-extract potential-allergen natural-origin

Frequently Asked Questions

Is Coprosma Grandifolia Leaf/Stem Extract safe in cosmetics?

Critical data gap identified. New Zealand endemic species (Rubiaceae family) with yellow/orange dye in inner bark; potential staining and colorant concerns. No published dermal toxicity, sensitization, or irritation data available. Requires full toxicological dossier including acute dermal toxicity, irritation, sensitization, and genotoxicity studies before CPSR acceptance. Extraction solvent, standardization, and botanical authentication must be specified. The EU classifies Coprosma Grandifolia Leaf/Stem Extract as "permitted". Safety rating: MODERATE.

Is Coprosma Grandifolia Leaf/Stem Extract allowed in the EU?

Coprosma Grandifolia Leaf/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coprosma Grandifolia Leaf/Stem Extract do in cosmetics?

Coprosma Grandifolia Leaf/Stem Extract functions as: Skin conditioning; traditional Māori medicine for skin diseases, stomach aches, wounds. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (rare botanical extract).

What is the Margin of Safety for Coprosma Grandifolia Leaf/Stem Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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