Coptis Chinensis Rhizome Extract

INCI: COPTIS CHINENSIS RHIZOME EXTRACT

CAS Number
Not specifically assigned for the full extract (berberine CAS: 2086-83-1 is a major constituent)
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: Not specifically restricted. Listed in CosIng and IECIC (China). EWG safety score 1 (low hazard). No CIR monograph for this specific extract.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Berberine content should be standardized and declared due to documented pharmacological activity (antimicrobial, anti-inflammatory) at high concentrations; palmatine co-extraction should be monitored. Solvent residue testing required based on extraction method. Yellow coloration may stain formulations; used as antioxidant in sunscreen formulations.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Coptis Chinensis Rhizome Extract safe in cosmetics?

Berberine content should be standardized and declared due to documented pharmacological activity (antimicrobial, anti-inflammatory) at high concentrations; palmatine co-extraction should be monitored. Solvent residue testing required based on extraction method. Yellow coloration may stain formulations; used as antioxidant in sunscreen formulations. The EU classifies Coptis Chinensis Rhizome Extract as "permitted". Safety rating: GOOD.

Is Coptis Chinensis Rhizome Extract allowed in the EU?

Coptis Chinensis Rhizome Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coptis Chinensis Rhizome Extract do in cosmetics?

Coptis Chinensis Rhizome Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for the full extract (berberine CAS: 2086-83-1 is a major constituent).

What is the Margin of Safety for Coptis Chinensis Rhizome Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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