Moderate Cosmetic Ingredient NOAEL Data

Curcuma Longa Leaf Extract

INCI: CURCUMA LONGA LEAF EXTRACT

CAS Number
84775-52-0
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: no specific restriction; CAS shared with other C. longa extracts

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Curcuma Longa Leaf Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 75 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
NOAEL 250 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 75 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
dose_tested 250 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

Different phytochemical profile than rhizome with higher terpene and lower curcuminoid content; essential oil content must be specified; potential IFRA-relevant components including camphor and 1,8-cineole; phototoxicity testing recommended

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

plant-extract essential-oil fda_food_additive

Frequently Asked Questions

Is Curcuma Longa Leaf Extract safe in cosmetics?

Different phytochemical profile than rhizome with higher terpene and lower curcuminoid content; essential oil content must be specified; potential IFRA-relevant components including camphor and 1,8-cineole; phototoxicity testing recommended The EU classifies Curcuma Longa Leaf Extract as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.

Is Curcuma Longa Leaf Extract allowed in the EU?

Curcuma Longa Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Curcuma Longa Leaf Extract do in cosmetics?

Curcuma Longa Leaf Extract functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84775-52-0.

What is the Margin of Safety for Curcuma Longa Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Curcuma Longa Leaf Extract?

The NOAEL (No Observed Adverse Effect Level) for Curcuma Longa Leaf Extract is 75 mg/kg bw/day based on a Short Term Toxicity study via oral route in mouse. A total of 4 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Curcuma Longa Leaf Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Curcuma Longa Leaf Extract in your formulation.