Moderate Cosmetic Ingredient

Cyanomethylphenyl Menthane Carboxamide

INCI: CYANOMETHYLPHENYL MENTHANE CARBOXAMIDE

CAS Number
Not identified in public registries under this exact name; related menthane‑3‑carboxamide: 68489‑14‑5 (N‑((ethoxycarbonyl)methyl)‑p‑menthane‑3‑carboxamide)
Function
Cooling agent / sensory modifier in the functional family of menthol derivatives and N-substituted menthane-3-carboxamides
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically regulated by name; would be treated as a novel cosmetic ingredient requiring manufacturer-held toxicology data. Related menthane-3-carboxamides have RIFM safety assessments for fragrance and flavour use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Eye irritation (GHS H319) and aquatic toxicity (H411) reported for related ethoxycarbonyl menthane-3-carboxamide; safety classification and laboratory testing required. Strong cooling and trigeminal stimulation potential warrants patch-testing and maximum-use concentration limits typical of cooling agents.

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Concern Level: High

Frequently Asked Questions

Is Cyanomethylphenyl Menthane Carboxamide safe in cosmetics?

Eye irritation (GHS H319) and aquatic toxicity (H411) reported for related ethoxycarbonyl menthane-3-carboxamide; safety classification and laboratory testing required. Strong cooling and trigeminal stimulation potential warrants patch-testing and maximum-use concentration limits typical of cooling agents. The EU classifies Cyanomethylphenyl Menthane Carboxamide as "permitted". Safety rating: MODERATE.

Is Cyanomethylphenyl Menthane Carboxamide allowed in the EU?

Cyanomethylphenyl Menthane Carboxamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyanomethylphenyl Menthane Carboxamide do in cosmetics?

Cyanomethylphenyl Menthane Carboxamide functions as: Cooling agent / sensory modifier in the functional family of menthol derivatives and N-substituted menthane-3-carboxamides. It is classified as a cosmetic ingredient in our database. CAS number: Not identified in public registries under this exact name; related menthane‑3‑carboxamide: 68489‑14‑5 (N‑((ethoxycarbonyl)methyl)‑p‑menthane‑3‑carboxamide).

What is the Margin of Safety for Cyanomethylphenyl Menthane Carboxamide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Cyanomethylphenyl Menthane Carboxamide compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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