Cyclo PEG-6

INCI: CYCLO PEG-6 (IF STANDALONE) / ASCORBYL CYCLO PEG-6 (THE REGISTERED DERIVATIVE)

CAS Number
Not publicly listed in CosIng or major databases as a standalone entry. The closely related derivative Ascorbyl Cyclo PEG-6 is registered in CosIng
Function
The ascorbyl derivative functions as a chelating agent - it binds trace metals to prevent product degradation, color changes, and breakdown of sensitive actives
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed (not listed among prohibited or restricted ingredients). As a PEG derivative, standard PEG purity concerns apply

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PEG-family compounds carry a general concern for potential 1,4-dioxane and ethylene oxide contamination from the ethoxylation process; manufacturers are expected to ensure purification to safe levels. The cyclic PEG-6 backbone offers improved chelation over linear PEGs. When conjugated with ascorbic acid, it stabilizes formulations by sequestering pro-oxidant metal ions

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Cyclo PEG-6 safe in cosmetics?

PEG-family compounds carry a general concern for potential 1,4-dioxane and ethylene oxide contamination from the ethoxylation process; manufacturers are expected to ensure purification to safe levels. The cyclic PEG-6 backbone offers improved chelation over linear PEGs. When conjugated with ascorbic acid, it stabilizes formulations by sequestering pro-oxidant metal ions The EU classifies Cyclo PEG-6 as "prohibited". Safety rating: MODERATE.

Is Cyclo PEG-6 allowed in the EU?

Cyclo PEG-6 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclo PEG-6 do in cosmetics?

Cyclo PEG-6 functions as: The ascorbyl derivative functions as a chelating agent - it binds trace metals to prevent product degradation, color changes, and breakdown of sensitive actives. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in CosIng or major databases as a standalone entry. The closely related derivative Ascorbyl Cyclo PEG-6 is registered in CosIng.

What is the Margin of Safety for Cyclo PEG-6?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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