Cyclodextrin Hydroxypropyltrimonium Chloride

INCI: CYCLODEXTRIN HYDROXYPROPYLTRIMONIUM CHLORIDE

CAS Number
Not widely published (cationic cyclodextrin derivative)
Function
Film forming, humectant, skin conditioning, viscosity controlling
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Quaternary ammonium derivatives can cause irritation at high concentrations in sensitive individuals. Not recommended for fragrance use. A cationically modified cyclodextrin bearing a hydroxypropyltrimonium chloride functional group. The cationic charge provides substantivity to negatively charged surfaces (skin and hair), enhancing deposition and conditioning. It combines the inclusion-complex capacity of cyclodextrins with the film-forming and conditioning benefits of quaternary ammonium ch...

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Concern Level: Moderate

Frequently Asked Questions

Is Cyclodextrin Hydroxypropyltrimonium Chloride safe in cosmetics?

Quaternary ammonium derivatives can cause irritation at high concentrations in sensitive individuals. Not recommended for fragrance use. A cationically modified cyclodextrin bearing a hydroxypropyltrimonium chloride functional group. The cationic charge provides substantivity to negatively charged surfaces (skin and hair), enhancing deposition and conditioning. It combines the inclusion-complex capacity of cyclodextrins with the film-forming and conditioning benefits of quaternary ammonium ch... The EU classifies Cyclodextrin Hydroxypropyltrimonium Chloride as "permitted". Safety rating: MODERATE.

Is Cyclodextrin Hydroxypropyltrimonium Chloride allowed in the EU?

Cyclodextrin Hydroxypropyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclodextrin Hydroxypropyltrimonium Chloride do in cosmetics?

Cyclodextrin Hydroxypropyltrimonium Chloride functions as: Film forming, humectant, skin conditioning, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (cationic cyclodextrin derivative).

What is the Margin of Safety for Cyclodextrin Hydroxypropyltrimonium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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