Good Cosmetic Ingredient

Cyclohexylcyclohexanone

INCI: CYCLOHEXYLCYCLOHEXANONE

CAS Number
Not clearly identified in public fragrance safety PDFs; analogs include 2‑ethyl‑4,4‑dimethylcyclohexanone and cyclohexanone ketals, which have RIFM safety assessments.
Function
Fragrance ingredient, providing woody/musk notes as an alicyclic ketone.
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific cosmetic restriction; subject to general safety obligations and any hazard communication rules.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Fragrance ingredient with potential eye and mucous membrane irritation; inhalation exposure assessment recommended for aerosols using Cramer-based TTC approach; control of unreacted cyclohexanone impurities.

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Cyclohexylcyclohexanone safe in cosmetics?

Fragrance ingredient with potential eye and mucous membrane irritation; inhalation exposure assessment recommended for aerosols using Cramer-based TTC approach; control of unreacted cyclohexanone impurities. The EU classifies Cyclohexylcyclohexanone as "permitted". Safety rating: GOOD.

Is Cyclohexylcyclohexanone allowed in the EU?

Cyclohexylcyclohexanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclohexylcyclohexanone do in cosmetics?

Cyclohexylcyclohexanone functions as: Fragrance ingredient, providing woody/musk notes as an alicyclic ketone.. It is classified as a cosmetic ingredient in our database. CAS number: Not clearly identified in public fragrance safety PDFs; analogs include 2‑ethyl‑4,4‑dimethylcyclohexanone and cyclohexanone ketals, which have RIFM safety assessments..

What is the Margin of Safety for Cyclohexylcyclohexanone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Cyclohexylcyclohexanone compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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