Cyclohydroxyprolyl Serine

INCI: CYCLOHYDROXYPROLYL SERINE

CAS Number
Not broadly published; may be proprietary to specific active suppliers.
Function
Skin-conditioning anti-ageing peptide active (firming, texture-improving), consistent with cyclic peptide use in cosmetics
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific restriction as cosmetic ingredient; treated as cosmetic active with standard safety substantiation expectation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novelty and lack of independent SCCS/CIR review; ensure full impurity profile (residual solvents, reagents), in vitro genotox data, and absence of endocrine activity; monitor for delayed hypersensitivity in post-marketing surveillance

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Concern Level: Low

Frequently Asked Questions

Is Cyclohydroxyprolyl Serine safe in cosmetics?

Novelty and lack of independent SCCS/CIR review; ensure full impurity profile (residual solvents, reagents), in vitro genotox data, and absence of endocrine activity; monitor for delayed hypersensitivity in post-marketing surveillance The EU classifies Cyclohydroxyprolyl Serine as "permitted". Safety rating: EXCELLENT.

Is Cyclohydroxyprolyl Serine allowed in the EU?

Cyclohydroxyprolyl Serine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclohydroxyprolyl Serine do in cosmetics?

Cyclohydroxyprolyl Serine functions as: Skin-conditioning anti-ageing peptide active (firming, texture-improving), consistent with cyclic peptide use in cosmetics. It is classified as a cosmetic ingredient in our database. CAS number: Not broadly published; may be proprietary to specific active suppliers..

What is the Margin of Safety for Cyclohydroxyprolyl Serine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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