Cyclopentadecanone

INCI: CYCLOPENTADECANONE

CAS Number
Commonly cited CAS for cyclopentadecanone macrocyclic ketone (exact CAS varies by isomer; RIFM safety assessment exists)
Function
Fragrance ingredient (macrocyclic musk-type ketone)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; considered safe for use in fragrance with RIFM/CIR-type review.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Possible sensitization in fragrance-allergic individuals; monitor IFRA restrictions if updated; review environmental profile as macrocyclic musk.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Cyclopentadecanone safe in cosmetics?

Possible sensitization in fragrance-allergic individuals; monitor IFRA restrictions if updated; review environmental profile as macrocyclic musk. The EU classifies Cyclopentadecanone as "permitted". Safety rating: GOOD.

Is Cyclopentadecanone allowed in the EU?

Cyclopentadecanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclopentadecanone do in cosmetics?

Cyclopentadecanone functions as: Fragrance ingredient (macrocyclic musk-type ketone). It is classified as a cosmetic ingredient in our database. CAS number: Commonly cited CAS for cyclopentadecanone macrocyclic ketone (exact CAS varies by isomer; RIFM safety assessment exists).

What is the Margin of Safety for Cyclopentadecanone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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