Cyclopia Intermedia Leaf Extract

INCI: CYCLOPIA INTERMEDIA LEAF EXTRACT

CAS Number
Not widely published (Cyclopia intermedia is a distinct honeybush species)
Function
Antioxidant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - botanical extract with no specific prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Similar profile to other Cyclopia species extracts; generally considered safe. Limited standalone clinical data compared to C. genistoides. Cyclopia intermedia is one of the four commercially harvested honeybush species in South Africa. Contains polyphenols including mangiferin and hesperidin, though the phytochemical profile differs quantitatively from C. genistoides. Traditionally used as a tea with antioxidant health benefits and topically for skin irritation

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Cyclopia Intermedia Leaf Extract safe in cosmetics?

Similar profile to other Cyclopia species extracts; generally considered safe. Limited standalone clinical data compared to C. genistoides. Cyclopia intermedia is one of the four commercially harvested honeybush species in South Africa. Contains polyphenols including mangiferin and hesperidin, though the phytochemical profile differs quantitatively from C. genistoides. Traditionally used as a tea with antioxidant health benefits and topically for skin irritation The EU classifies Cyclopia Intermedia Leaf Extract as "permitted". Safety rating: MODERATE.

Is Cyclopia Intermedia Leaf Extract allowed in the EU?

Cyclopia Intermedia Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclopia Intermedia Leaf Extract do in cosmetics?

Cyclopia Intermedia Leaf Extract functions as: Antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (Cyclopia intermedia is a distinct honeybush species).

What is the Margin of Safety for Cyclopia Intermedia Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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