Regulatory Status
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Safety Data
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Expert Verdict
Novel bioactive with incompletely characterized long-term effects and potential off-target signaling; requires robust impurity control and stability data.
Frequently Asked Questions
Is Cyclo(Prolylproline) safe in cosmetics?
Novel bioactive with incompletely characterized long-term effects and potential off-target signaling; requires robust impurity control and stability data. The EU classifies Cyclo(Prolylproline) as "prohibited". Safety rating: MODERATE.
Is Cyclo(Prolylproline) allowed in the EU?
Cyclo(Prolylproline) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyclo(Prolylproline) do in cosmetics?
Cyclo(Prolylproline) functions as: Skin-conditioning / anti-aging peptide; may influence extracellular matrix and firmness by peptide signaling. It is classified as a cosmetic ingredient in our database. CAS number: 3446‑89‑7 (commonly cited for cyclo(L‑Pro‑L‑Pro)); individual cosmetic grade materials may use supplier‑specific identifiers (screening judgement).
What is the Margin of Safety for Cyclo(Prolylproline)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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