Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl

INCI: CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE HCL

CAS Number
Not publicly listed in the sources reviewed (the free-base form is CAS 197172-76-2; the HCl salt may not have a separately assigned CAS in cosmetic databases)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. No specific restrictions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low concern; same peptide backbone as ingredient \#4, presented as the hydrochloride salt for improved water solubility/stability.. HCl salt form of ingredient \#4. The salt form typically offers improved aqueous solubility and formulation stability compared to the free carboxylate, making it easier to incorporate into water-phase formulations. Functions as a skin conditioning agent rather than the antioxidant function attributed to the free base.

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Concern Level: Moderate

Frequently Asked Questions

Is Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl safe in cosmetics?

Low concern; same peptide backbone as ingredient \#4, presented as the hydrochloride salt for improved water solubility/stability.. HCl salt form of ingredient \#4. The salt form typically offers improved aqueous solubility and formulation stability compared to the free carboxylate, making it easier to incorporate into water-phase formulations. Functions as a skin conditioning agent rather than the antioxidant function attributed to the free base. The EU classifies Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl as "permitted". Safety rating: MODERATE.

Is Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl allowed in the EU?

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl do in cosmetics?

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in the sources reviewed (the free-base form is CAS 197172-76-2; the HCl salt may not have a separately assigned CAS in cosmetic databases).

What is the Margin of Safety for Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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