Cynara Scolymus Leaf Extract

INCI: CYNARA SCOLYMUS LEAF EXTRACT

CAS Number
84012-14-6
Function
Skin Conditioning, Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restrictions; no CIR final report published

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted in EU and US with no Annex restrictions; dermal absorption and sensitization studies needed for CPSR; potential Asteraceae cross-reactivity warrants allergy consideration.

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Concern Level: Low

Regulatory Flags

no-sccs-opinion no-cir-monograph asteraceae-cross-reactivity compositae-allergen-flag data-gaps

Frequently Asked Questions

Is Cynara Scolymus Leaf Extract safe in cosmetics?

Permitted in EU and US with no Annex restrictions; dermal absorption and sensitization studies needed for CPSR; potential Asteraceae cross-reactivity warrants allergy consideration. The EU classifies Cynara Scolymus Leaf Extract as "permitted". Safety rating: GOOD.

Is Cynara Scolymus Leaf Extract allowed in the EU?

Cynara Scolymus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cynara Scolymus Leaf Extract do in cosmetics?

Cynara Scolymus Leaf Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84012-14-6.

What is the Margin of Safety for Cynara Scolymus Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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