CYSTEINE HCL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
10 study endpoints found for CYSTEINE HCL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 100 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 8000 mg/kg bw/day | oral | rat | Multigeneration Reproductive | COSMOS_DB |
| NOAEL | 13 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | ca.175 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | ca.600 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 500 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >600 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
CYSTEINE HCL is listed in the EU CosIng database with functions: Antioxidant, Hair Conditioning, Hair Waving Or Straightening, Reducing It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is CYSTEINE HCL safe in cosmetics?
CYSTEINE HCL is listed in the EU CosIng database with functions: Antioxidant, Hair Conditioning, Hair Waving Or Straightening, Reducing It is permitted in the EU without specific restrictions. The EU classifies CYSTEINE HCL as "Permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is CYSTEINE HCL allowed in the EU?
CYSTEINE HCL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CYSTEINE HCL do in cosmetics?
CYSTEINE HCL functions as: Antioxidant, Hair Conditioning, Hair Waving Or Straightening, Reducing. It is classified as a cosmetic ingredient in our database. CAS number: 52-89-1.
What is the NOAEL for CYSTEINE HCL?
The NOAEL (No Observed Adverse Effect Level) for CYSTEINE HCL is 3000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check CYSTEINE HCL compliance across multiple jurisdictions:
Related Ingredients
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