Good Cosmetic Ingredient

Cysteine/Oligomeric Proanthocyanidin

INCI: CYSTEINE/OLIGOMERIC PROANTHOCYANIDIN

CAS Number
Not uniquely assigned; complex of cysteine and oligomeric proanthocyanidins (OPCs) from plant sources; treated as a mixture
Function
Skin conditioning agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA restriction; allowed as a cosmetic skin-conditioning ingredient if safe; plant polyphenol complex may be considered GRAS-like in food but must be substantiated for topical use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Batch-to-batch variability requires control for pesticide residues, solvent residues, and heavy metals; monitor for rare plant-allergy reactions

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Cysteine/Oligomeric Proanthocyanidin safe in cosmetics?

Batch-to-batch variability requires control for pesticide residues, solvent residues, and heavy metals; monitor for rare plant-allergy reactions The EU classifies Cysteine/Oligomeric Proanthocyanidin as "permitted". Safety rating: GOOD.

Is Cysteine/Oligomeric Proanthocyanidin allowed in the EU?

Cysteine/Oligomeric Proanthocyanidin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cysteine/Oligomeric Proanthocyanidin do in cosmetics?

Cysteine/Oligomeric Proanthocyanidin functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned; complex of cysteine and oligomeric proanthocyanidins (OPCs) from plant sources; treated as a mixture.

What is the Margin of Safety for Cysteine/Oligomeric Proanthocyanidin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Cysteine/Oligomeric Proanthocyanidin compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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