Cytochrome C

INCI: CYTOCHROME C

CAS Number
9007‑43‑6 (commonly referenced for cytochrome c from equine/other sources)
Function
Antioxidant, mitochondrial-associated peptide; marketed as anti-aging, anti-wrinkle active in topical products
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted for cosmetic use; subject to general safety requirement. Avoid therapeutic claims that would classify as drug or biologic.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Proteinaceous peptide with potential immunogenicity risk. Product should avoid application on broken skin and maintain adequate preservation to control microbial growth.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Cytochrome C safe in cosmetics?

Proteinaceous peptide with potential immunogenicity risk. Product should avoid application on broken skin and maintain adequate preservation to control microbial growth. The EU classifies Cytochrome C as "permitted". Safety rating: MODERATE.

Is Cytochrome C allowed in the EU?

Cytochrome C EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cytochrome C do in cosmetics?

Cytochrome C functions as: Antioxidant, mitochondrial-associated peptide; marketed as anti-aging, anti-wrinkle active in topical products. It is classified as a cosmetic ingredient in our database. CAS number: 9007‑43‑6 (commonly referenced for cytochrome c from equine/other sources).

What is the Margin of Safety for Cytochrome C?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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