D-Nonapeptide-2

INCI: D-NONAPEPTIDE-2

CAS Number
Not identified in public cosmetic databases; likely assigned in supplier documentation
Function
Cosmetic peptide used for anti-ageing, skin-firming, or pigmentation-related applications based on nonapeptide family usage and dermal ECM modulation
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; evaluated under general FDA cosmetic safety standards

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Independent SCCS/CIR evaluation is absent; verification needed for off-target pharmacology, genotoxicity, and systemic toxicity risks, particularly for high-concentration serums applied over large body areas

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Concern Level: Moderate

Frequently Asked Questions

Is D-Nonapeptide-2 safe in cosmetics?

Independent SCCS/CIR evaluation is absent; verification needed for off-target pharmacology, genotoxicity, and systemic toxicity risks, particularly for high-concentration serums applied over large body areas The EU classifies D-Nonapeptide-2 as "permitted". Safety rating: MODERATE.

Is D-Nonapeptide-2 allowed in the EU?

D-Nonapeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does D-Nonapeptide-2 do in cosmetics?

D-Nonapeptide-2 functions as: Cosmetic peptide used for anti-ageing, skin-firming, or pigmentation-related applications based on nonapeptide family usage and dermal ECM modulation. It is classified as a cosmetic ingredient in our database. CAS number: Not identified in public cosmetic databases; likely assigned in supplier documentation.

What is the Margin of Safety for D-Nonapeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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