Moderate Cosmetic Ingredient

DEA‑Isostearate

INCI: DEA-ISOSTEARATE

CAS Number
Not uniquely defined in major public inventories; often treated under generic “diethanolamine fatty acid amides” group; CAS not reliably established for CPSR use (data gap).
Function
Surfactant, foam booster, viscosity increasing agent, potential emulsifying and conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes No specific FDA cosmetic ingredient restriction on DEA-Isostearate; however, FDA has expressed concern about DEA-containing ingredients and nitrosamine formation. CIR evaluated diethanolamides as a group and concluded amides safe as used when formulated to be non-irritating and when free DEA is tightly limited.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

DEA-Isostearate carries potential for free DEA release (CMR 2 in EU), nitrosamine formation risk in presence of nitrosating agents, irritation potential in surfactant systems, and regulatory pressure to avoid DEA derivatives in EU-bound products.

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Concern Level: Moderate

Frequently Asked Questions

Is DEA‑Isostearate safe in cosmetics?

DEA-Isostearate carries potential for free DEA release (CMR 2 in EU), nitrosamine formation risk in presence of nitrosating agents, irritation potential in surfactant systems, and regulatory pressure to avoid DEA derivatives in EU-bound products. The EU classifies DEA‑Isostearate as "restricted". Safety rating: MODERATE.

Is DEA‑Isostearate allowed in the EU?

DEA‑Isostearate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does DEA‑Isostearate do in cosmetics?

DEA‑Isostearate functions as: Surfactant, foam booster, viscosity increasing agent, potential emulsifying and conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely defined in major public inventories; often treated under generic “diethanolamine fatty acid amides” group; CAS not reliably established for CPSR use (data gap)..

What is the Margin of Safety for DEA‑Isostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check DEA‑Isostearate compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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