Moderate Cosmetic Ingredient

Decapeptide-16

INCI: DECAPEPTIDE-16

CAS Number
Not clearly reported; likely proprietary/supplier‑level CAS, not broadly indexed
Function
Presumed skin conditioning or signaling peptide, in line with cosmetic decapeptide use for anti-ageing and repair support
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted as a cosmetic ingredient; not separately regulated; subject to general FDA cosmetic safety provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Key concern is data gap; avoid high-exposure categories (sprays with inhalation, lip products, peri-ocular use) until more toxicology data are available; keep inclusion levels in low ppm range and document supplier toxicology support in CPSR

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Decapeptide-16 safe in cosmetics?

Key concern is data gap; avoid high-exposure categories (sprays with inhalation, lip products, peri-ocular use) until more toxicology data are available; keep inclusion levels in low ppm range and document supplier toxicology support in CPSR The EU classifies Decapeptide-16 as "permitted". Safety rating: MODERATE.

Is Decapeptide-16 allowed in the EU?

Decapeptide-16 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decapeptide-16 do in cosmetics?

Decapeptide-16 functions as: Presumed skin conditioning or signaling peptide, in line with cosmetic decapeptide use for anti-ageing and repair support. It is classified as a cosmetic ingredient in our database. CAS number: Not clearly reported; likely proprietary/supplier‑level CAS, not broadly indexed.

What is the Margin of Safety for Decapeptide-16?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Decapeptide-16 compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Tripeptide-72
Moderate
Tetrapeptide-28
Moderate
Leucanthemum Vulgare Seed Extract
Moderate
Hydroxymethoxyiodobenzyl Glycolamide Caprate
Moderate
Achillea Millefolium Flower/Leaf/Stem Juice
Moderate
Browse all 30,000+ ingredients →
📱

Is Decapeptide-16 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Decapeptide-16 in your formulation.

Ingredient Decoder MoS Calculator